Trafficking of Ganglioside GD3 to Mitochondria by Tumor Necrosis Factor-α
نویسندگان
چکیده
منابع مشابه
Hemorrhagic Tumor Necrosis During a Pilot Trial of Tumor Necrosis Factor-a and Anti-GD3 Ganglioside Monoclonal Antibody
Hemorrhagic tumor necrosis is an inflammatory event that leads to selective destruction of malignant tissues, with both potentially toxic and beneficial consequences. A pilot clinical trial was undertaken combining tumor necrosis factor-a (TNF-a) with the monoclonal antibody R 2 4 (MoAb R 2 4 ) against GD3 ganglioside in patients with metastatic melanoma. Patients received MoAb R 2 4 to recruit...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 2002
ISSN: 0021-9258
DOI: 10.1074/jbc.m206021200